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J H Scholefield Selected Research

Fissure in Ano (Anal Fissure)

10/2005Comparison of the effects of nitric oxide donors and calcium channel blockers on the intrinsic myogenic tone of sheep isolated internal anal sphincter.
9/2003L-arginine-induced relaxation of the internal anal sphincter is not mediated by nitric oxide.
11/2002The role of topical diltiazem in the treatment of chronic anal fissures that have failed glyceryl trinitrate therapy.
10/2002Topical L-arginine gel lowers resting anal pressure: possible treatment for anal fissure.
9/2002Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17).
8/2001A randomized trial of oral vs. topical diltiazem for chronic anal fissures.
3/2001Anal Fissure.

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J H Scholefield Research Topics

Disease

9Colorectal Neoplasms (Colorectal Cancer)
10/2005 - 02/2000
7Fissure in Ano (Anal Fissure)
10/2005 - 03/2001
5Rectal Neoplasms (Rectal Cancer)
03/2009 - 02/2000
4Neoplasms (Cancer)
11/2004 - 04/2000
3Inflammation (Inflammations)
04/2012 - 04/2008
3Headache (Headaches)
10/2002 - 08/2001
2Diverticular Diseases
04/2012 - 08/2009
2Hypersensitivity (Allergy)
04/2012 - 08/2009
2Adenoma (Adenomas)
12/2009 - 06/2000
2Colitis
08/2009 - 04/2008
2Diverticulitis
08/2009 - 04/2008
1Pain (Aches)
03/2017
1Fistula
03/2017
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2017
1Abdominal Pain (Pain, Abdominal)
04/2008
1Fibrosarcoma
10/2005
1Colonic Neoplasms (Colon Cancer)
03/2002
1Exanthema (Rash)
08/2001
1Nausea
08/2001
1Vomiting
08/2001
1Residual Neoplasm
06/2001
1Hernia (Hernias)
05/2001
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
03/2001
1Ileus
06/2000
1Carcinoma (Carcinomatosis)
06/2000

Drug/Important Bio-Agent (IBA)

4Proteins (Proteins, Gene)FDA Link
08/2009 - 02/2000
3NeuropeptidesIBA
04/2012 - 04/2008
3Diltiazem (Cardizem)FDA LinkGeneric
11/2002 - 08/2001
2TachykininsIBA
04/2012 - 04/2008
2Substance PIBA
08/2009 - 04/2008
2GalaninIBA
08/2009 - 04/2008
2Matrix Metalloproteinases (MMPs)IBA
10/2005 - 03/2002
2GelatinIBA
10/2005 - 02/2000
2Arginine (L-Arginine)FDA Link
09/2003 - 10/2002
2Nitroglycerin (Dynamite)FDA LinkGeneric
10/2002 - 09/2002
2VaccinesIBA
06/2001 - 06/2000
2Cancer VaccinesIBA
06/2001 - 06/2000
2Monoclonal AntibodiesIBA
06/2001 - 04/2000
2AntigensIBA
06/2001 - 04/2000
1Serotonin (5 Hydroxytryptamine)IBA
04/2012
1Calcibiotic Root Canal SealerIBA
12/2009
1Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA
08/2009
1neuropeptide KIBA
08/2009
1Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA
08/2009
1AcidsIBA
04/2008
1Calcium Channel Blockers (Blockers, Calcium Channel)IBA
10/2005
1Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2003
1Nitric Oxide DonorsIBA
10/2002
1Messenger RNA (mRNA)IBA
03/2002
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
03/2002
1Matrix Metalloproteinase 7 (Matrilysin)IBA
03/2002
1A-factor (Streptomyces)IBA
01/2002
1Ointments (Pastes)IBA
12/2001
1CD55 Antigens (Decay Accelerating Factor)IBA
06/2001
1Biological ProductsIBA
06/2000
1Leukocyte L1 Antigen Complex (Calgranulin)IBA
06/2000
1CytokinesIBA
04/2000
1Complement System Proteins (Complement)IBA
04/2000
1105AD7 antibodyIBA
02/2000
1Collagenases (Collagenase)FDA Link
02/2000

Therapy/Procedure

3Therapeutics
03/2017 - 08/2001
3Immunotherapy
04/2002 - 04/2000
3Radiotherapy
03/2002 - 02/2000
2Sphincterotomy
08/2001 - 03/2001
1Chemoradiotherapy
03/2017
1Colostomy
03/2017
1Brachytherapy
03/2017
1Aftercare (After-Treatment)
03/2017
1Nursing Care
03/2009
1Photochemotherapy (Photodynamic Therapy)
11/2004
1Ileostomy
05/2001
1Laparotomy
05/2001
1Sutures (Suture)
05/2001
1Analgesia
06/2000